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  • On the possibility of using optoacoustic methods for studying the properties of biological tissues (review)

    The optoacoustic effect used for imaging can provide improved spatial resolution and temperature sensitivity compared to other methods of non-invasive cytometry, thermometry, used during thermal therapy for safe and effective diagnosis. However, the accuracy of the described optoacoustic methods is reduced due to biological variability and heterogeneous composition of tissues. Optoacoustic spectral analysis is used to assess the morphological changes of red blood cells (for example, size / shape).

    Keywords: optoacoustics, optoacoustic signal, biofluid, oxygenation, hemoglobin, erythrocyte

  • On the possibility of using optoacoustic methods for studying the properties of biological tissues

    The measurement of the total concentration of hemoglobin in the blood is widely used both in the general analysis to assess the general condition of a person, and during an operation associated with rapid blood loss, blood transfusions, or rapid fluid administration. Although current invasive methods for measuring hemoglobin are accurate, they require frequent blood sampling and some time to obtain results from a remote laboratory. Moreover, taking blood is often not an acceptable option for patients with surgery, as this can help reduce anemia. Optoacoustic method can be a good alternative to invasive methods

    Keywords: optoacoustics, optoacoustic waves, biofluids, oxygen saturation, hemoglobin

  • Investigation of the profile of the optoacoustic signal in biological tissues

    Optoacoustic acoustic transients arising from optical absorption and thermoelastic expansion contain information on the optical properties of the irradiated medium. The profile of the optoacoustic signal generated by the absorber, for example from cancer cells, has a complex geometric structure, can be represented by the convolution of acoustic waves emitted by a number of small spherical sources.

    Keywords: optoacoustics, optoacoustic waves, absorption, spherical absorber

  • Features of the formation of optoacoustic waves in biological tissues

    In work methods of generation of an optoacoustic signal for studying biological tissues are considered, the advantages of the method are shown. Ultrasound studies of biotissues are based on the detection of mechanical properties in biological tissues, ultrasonic methods do not allow to establish the level of oxygen saturation or hemoglobin concentration. Optoacoustic methods can allow to determine the properties of tissues and give images with high contrast at high ultrasound resolution in relatively large volumes of biological tissues.

    Keywords: optoacoustics, optoacoustic waves, biofluids, spherical sources, absorption, oxygen saturation, near field, far field

  • On the possibility of detecting viruses with an optoacoustic method using carbon nanoparticles

    The possibility of detecting viruses in biomedical research using the optoacoustic method with carbon nanotubes is considered in the paper. In this paper, we consider the setup used to detect optoacoustic responses from a sample, which allows the recording of optical-acoustic signals generated by carbon nanotubes attached to the surface of viruses in the blood and which have high optical absorption. When the sample is irradiated, the absorbed energy from the laser radiation is converted into kinetic energy by means of energy exchange processes. This leads to local heating and, consequently, to the appearance of a wave of sound pressure. By recording ultrasonic waves, it is possible to form a spectrum of the optoacoustic signal for the test sample, which can be used to detect the absorbing components in it.

    Keywords: diversification of management, production diversification, financial and economic purposes of a diversification, technological purposes of ensuring flexibility of production

  • Analytical result of generation of optoacoustic waves for spherical absorbers in the distant field

    In operation analytical expressions of amplitude of sound pressure for spherical absorbers as a result of influence of a laser radiation in liquid in a distant field are received. The thermooptoacoustic effect leads to excitation of acoustic waves in case of absorption of a variable luminous flux. It is shown that the optoacoustic effects watched in the liquid environments are beyond the osnovopolakgayushchikh of the developed models for the ideal environments and require more detailed reviewing and specification.

    Keywords: optoacoustics, optoacoustic waves, bioliquid, cylindrical, spherical absorbers

  • Application of optoacoustic methods in biomedical research

    Methods based on the thermo-optoacoustic effect in a liquid for conducting biomedical research are considered in the work. The mechanisms participating in the formation of the optoacoustic signal are considered. Thermo-opoacoustic effect leads to the excitation of ultrasonic waves when absorbing a variable light flux. Numerical methods for calculating the optoacoustic effect that can be applied to energy calculations and conditions of a source with arbitrary geometry, to the construction of a temporal profile of laser radiation, to linear scanning of a laser source and tomography are considered.

    Keywords: optoacoustics, optoacoustic waves, biofluids, spherical sources, absorption.

  • Optoacoustics, nanofibres, optoacoustic waves, biofluids, virtual instrument, signal spectrum, spherical reflectors.

    In operation the optico-acoustical effect which leads to excitation of acoustic waves in case of absorption of a variable luminous flux is considered. The model of calculation of the acoustic field generated by a laser study in liquid in case of hit on cylindrical objects in liquid is offered. The special nanomaterials added to liquid can serve as cylindrical objects. It is set that the optoacoustic effects watched in the liquid environments are beyond the fundamental developed models for the ideal environments and require more detailed reviewing and specification.

    Keywords: optoacoustics, optoacoustic waves, bioliquid, virtual device, cylindrical, spherical absorbers, nanofibres

  • Experimental research and modeling of the process of generation of an optoacoustic signal

    The optical-acoustic effect, which leads to the excitation of acoustic waves upon absorption of a variable light flux, is considered. A model is proposed for calculating the acoustic field generated by a laser study in a liquid when it hits a spherical object in savagery. Spherical objects can serve as special nanomaterials added to the liquid. The results of an experiment on the excitation of an optoacoustic signal in a liquid by means of a laser for laser flow diagnostics are presented. Since the laser beam is characterized by a set of parameters: power, polarization, wavelength, frequency, phase and direction of propagation, then by changing these parameters one can judge the processes occurring in the investigated stream.

    Keywords: optoacoustics, nanofibres, optoacoustic waves, biofluids, virtual instrument, signal spectrum, spherical reflectors