Development of a mathematical model of an automated control system for the technological process of obtaining E. coli
Abstract
Development of a mathematical model of an automated control system for the technological process of obtaining E. coli
Incoming article date: 18.10.2022The article is devoted to the research and development of an automated control system for the technological process of obtaining E. coli. E. coli belongs to gram-negative rod-shaped bacteria of the Enterobacteriaceae family of facultative anaerobes. It is the most famous microbe in the world and has different types of strains. Commensal E.coli are harmless and often found in nature. Currently, great attention is paid to the use of modified E.coli for the production of recombinant proteins, amino acids. The results of mathematical modeling of the automated system are presented. The simulation was performed using SimInTech and MathCAD software tools. The object of management is the cultivation capacity. The temperature of the Escherichia coli is accepted as a regulated technological parameter, which is controlled by changing the degree of valve opening. The method of passive experiment was used to build an automated control system. The main parameters of the control object are obtained.
Keywords: automated control system, technological process, E. coli, mathematical modeling, control object, transfer function, control parameters